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Identifying the Challenges in AutomationĪlthough the benefits of automation are vast, many labs are intimidated by the costs and technical complexity. Third, the company is rapidly growing its teams and wants its new employees to focus on scientific discovery and innovation, not spinning plates and moving liquids. With a fully automated system, scientists have a complete data capture of every single step in the process. Second, Beam wanted FAIR data capture without putting the burden on its scientists. With automation, the scale of their experimentation changes – they can test more variables, increase reps to power statistics, and ultimately accomplish more with smaller volumes in less time. While automation’s ROI is well known – the ability to miniaturise experiments and increase walk-away time and instrument utilisation – Beam also understood how automation could empower its scientists.įirst, Beam wanted to establish a culture of automation amongst its scientists as it would alter the way they design experiments. The company knew that the most effective and efficient path to advancing this mission was through automation. What are the Benefits of Automation?īeam’s mission is to leverage its cutting-edge science to provide life-long cures to patients suffering from serious diseases.
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So, Beam sought to go from manual to fully automated immediately so it could realise all of the benefits of automation routinely in its day-to-day operations.
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However, companies such as Beam Therapeutics, a biotechnology company pioneering the use of base editing, evaluated its return on investment (ROI) differently – it understood that the greatest drivers of operating costs – personnel and space – are actually best used with automation. Finally, it moves to a fully automated system with robots, liquid handlers and an array of instruments.ĭue to costs or technical challenges, labs typically go through this process stage-by-stage. Then, it moves towards a semi-automated system that typically includes a liquid handler and an analytical instrument such as a plate reader. 3 Stages of the Automation Journeyįor most companies, the automation journey is broken down into three stages. As a result, biotech companies are faced with how they should adopt automation instead of whether they should or not. Instead, new tech-forward biotech companies are implementing these systems as they seek to address a labour shortage of skilled technicians, accelerate their discoveries and enable their scientists to focus on their next idea.
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With costs going down, integrators reducing the burden on teams and new software tools that capture data or connect instrumentation, fully automated systems are no longer only installed at high-throughput screening labs and Big Pharma screening groups. Nikhita Singh presents a case study that explores how one company has overcome the challenge of accessibility in lab automation.